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Year : 2021  |  Volume : 8  |  Issue : 2  |  Page : 152-158

Can ovarian stromal blood flow predict the response to stimulation in polycystic ovary syndrome patients undergoing infertility treatment

KJIVF and Laparoscopy Centre, Delhi, India

Correspondence Address:
Dr. Ruchika Sood
KJIVF and Laparoscopy Centre, 23-24 Gagan Vihar, Delhi 110051
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/fsr.fsr_19_21

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Aim: To find out the difference in ovarian stromal blood flow in polycystic ovary syndrome (PCOS) and non-PCOS infertile patient and role of ovarian stromal blood flow as predictor of follicular response. Design: Prospective study. Setting: KJIVF and Laparoscopy Centre, Delhi. Materials and methods: Total 120 patients were recruited and divided into two equal groups. PCOS and non-PCOS infertile women of less than 35 years of age undergoing intrauterine insemination and in vitro fertilization (IVF) were included. Baseline and poststimulation two-dimensional transvaginal ultrasound with color and power Doppler was performed. Blood flow velocity waveforms with optimal flow were selected for measurement of systolic/diastolic ratio, peak systolic velocity (PSV), pulsatility index, and resistive index. Intervention: Color Doppler for ovarian stromal blood flow. Statistical analysis: Statistical testing was performed with the statistical package for the social science system version SPSS 17.0. Results: (a) Day 2/3 ovarian stromal PSV was significantly higher in PCOS women when compared with non-PCOS. (b) Positive correlation between ovarian stromal PSV and follicular response in patients with both PCOS and non-PCOS. Conclusion: Stromal vascularity in PCOS can be used as an additional criterion for the diagnosis of PCOS and ovarian stromal blood flow can be used as predictor of follicular response in IVF cycles especially in patients with PCOS.

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