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EDITORIAL
Year : 2021  |  Volume : 8  |  Issue : 2  |  Page : 105-110

Male factor in recurrent pregnancy loss


IVF and Reproductive Medicine, Max Multispeciality Hospital, Delhi, India

Correspondence Address:
Dr. Surveen Ghumman
IVF and Reproductive Medicine, Max Multispeciality Hospital, B 517, New Friends Colony, New Delhi 110025
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/fsr.fsr_46_21

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Miscarriage word seems to signify that only women are involved. However miscarriage may be the result of a faulty gamete −male or female. Karyotyping should be carried out if there are two or more miscarriages. In vitro fertilization and preimplantation genetic screening may be carried out in these cases. Prenatal diagnosis has a place in recurrent pregnancy losses (RPL) and should be performed when a translocation or other abnormalities are detected. Men should be given therapy in the form of antioxidants and lifestyle changes that improve overall health and sperm function. In case of obese, men they should loose weight. Regular exercise is important. Diet should be rich in fresh fruits and vegetables. They should limit alcohol and quit smoking. Regular vitamins should be taken. Male factor could be an important cause of embryonic mortality and RPL and should be addressed in all these cases. Hence, more in depth knowledge of epigenetics and genetics is required. As sperm aneuploidy and DNA fragmentation have been shown to be responsible in some cases, it is imperative to have reliable tests for diagnosis of sperm aneuploidy and DNA fragmentation.


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